Invention Grant
- Patent Title: Ethynyl derivatives
- Patent Title (中): 乙炔衍生物
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Application No.: US13628128Application Date: 2012-09-27
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Publication No.: US08530472B2Publication Date: 2013-09-10
- Inventor: Georg Jaeschke , Lothar Lindemann , Antonio Ricci , Daniel Rueher , Heinz Stadler , Eric Vieira
- Applicant: Hoffmann-La Roche Inc.
- Applicant Address: US NJ Nutley
- Assignee: Hoffmann-La Roche Inc.
- Current Assignee: Hoffmann-La Roche Inc.
- Current Assignee Address: US NJ Nutley
- Priority: EP11184257 20111007
- Main IPC: A61K31/505
- IPC: A61K31/505 ; A61K31/50 ; A61K31/44 ; C07D237/02 ; C07D239/02 ; C07D211/00
Abstract:
The present invention relates to ethynyl derivatives of formula I wherein U, V, W, Y, R, R1, R2, R3 and R3′ are as described herein. It has been found that the compounds of general formula I are allosteric modulators of the metabotropic glutamate receptor subtype 5 (mGluR5).
Public/Granted literature
- US20130090347A1 ETHYNYL DERIVATIVES Public/Granted day:2013-04-11
Information query
