Invention Grant
US08530474B2 Substituted 6-(1-piperazinyl)-pyridazines as 5-HT6 receptor antagonists
有权
取代的6-（1-哌嗪基） - 哒嗪作为5-HT 6受体拮抗剂
- Patent Title: Substituted 6-(1-piperazinyl)-pyridazines as 5-HT6 receptor antagonists
- Patent Title (中): 取代的6-（1-哌嗪基） - 哒嗪作为5-HT 6受体拮抗剂
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Application No.: US13002413Application Date: 2009-07-01
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Publication No.: US08530474B2Publication Date: 2013-09-10
- Inventor: José Manuel Bartolomé-Nebreda , Gregor James MacDonald , Michiel Luc Maria Van Gool , Susana Conde-Ceide , Francisca Delgado-Jiménez
- Applicant: José Manuel Bartolomé-Nebreda , Gregor James MacDonald , Michiel Luc Maria Van Gool , Susana Conde-Ceide , Francisca Delgado-Jiménez
- Applicant Address: BE Beerse
- Assignee: Janssen Pharmaceutica NV
- Current Assignee: Janssen Pharmaceutica NV
- Current Assignee Address: BE Beerse
- Agent Hal B. Woodrow
- Priority: EP08159591 20080703
- International Application: PCT/EP2009/004745 WO 20090701
- International Announcement: WO2010/000456 WO 20100107
- Main IPC: A61K31/50
- IPC: A61K31/50 ; A61K31/501
Abstract:
The present invention is concerned with novel substituted 6-(1-piperazinyl)-pyridazines of Formula (I) wherein R1, R2, R3 and X have the meaning defined in the claims, having 5-HT6-antagonistic properties. The invention further relates to processes for preparing such novel compounds, pharmaceutical compositions comprising said novel compound as an active ingredient as well as the use of said compounds as a medicine.
Public/Granted literature
- US20110112107A1 SUBSTITUTED 6-(1-PIPERAZINYL)-PYRIDAZINES AS 5-HT6 RECEPTOR ANTAGONISTS Public/Granted day:2011-05-12
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