Invention Grant
- Patent Title: Bicyclic cyclohexitol nucleic acid analogs
- Patent Title (中): 双环体醇核酸类似物
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Application No.: US12866708Application Date: 2009-02-06
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Publication No.: US08530640B2Publication Date: 2013-09-10
- Inventor: Punit P. Seth , Michael T. Migawa , Eric E. Swayze , Quanlai Song , Mingming Han , Bruce S. Ross
- Applicant: Punit P. Seth , Michael T. Migawa , Eric E. Swayze , Quanlai Song , Mingming Han , Bruce S. Ross
- Applicant Address: US CA Carlsbad
- Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee: Isis Pharmaceuticals, Inc.
- Current Assignee Address: US CA Carlsbad
- Agency: Isis Pharmaceuticals, Inc. Patent Dept.
- International Application: PCT/US2009/033373 WO 20090206
- International Announcement: WO2009/100320 WO 20090813
- Main IPC: C07H19/24
- IPC: C07H19/24 ; C07H19/04

Abstract:
The present disclosure provides bicyclic cyclohexitol nucleoside analogs of formula I and oligomeric compounds comprising these nucleoside analogs. These bicyclic nucleoside analogs are expected to be useful for enhancing properties of oligomeric compounds including for example nuclease resistance.
Public/Granted literature
- US20110077390A1 BICYCLIC CYCLOHEXITOL NUCLEIC ACID ANALOGS Public/Granted day:2011-03-31
Information query
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