Invention Grant
- Patent Title: Method for removing impurities from biopolymer material
- Patent Title (中): 从生物聚合物材料中除去杂质的方法
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Application No.: US12999565Application Date: 2008-06-19
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Publication No.: US08530644B2Publication Date: 2013-09-10
- Inventor: Johannes Caspar Mathias Elizabeth Bender , Pieter Sebastiaan Vermeulen
- Applicant: Johannes Caspar Mathias Elizabeth Bender , Pieter Sebastiaan Vermeulen
- Applicant Address: NL Utrecht
- Assignee: Bender Analytical Holding B.V.
- Current Assignee: Bender Analytical Holding B.V.
- Current Assignee Address: NL Utrecht
- Agency: Foley & Lardner LLP
- Agent Gilberto M. Villacorta; Sunit Talapatra
- International Application: PCT/NL2008/050396 WO 20080619
- International Announcement: WO2009/154440 WO 20091223
- Main IPC: C07H1/06
- IPC: C07H1/06 ; C07H1/08

Abstract:
The present invention relates to a method for removing impurities from biopolymer material, e.g. polysaccharides, polypeptides or polynucleotides. More particularly, the present invention provides a method of reducing lipopolysaccharide levels in a lipopolysaccharide containing biopolymer material, comprising the successive steps of: a) providing an aqueous solution containing 0.05-50 wt. % of dissolved lipopolysaccharide-containing biopolymer material; 0.001-10 wt.% of a surfactant; 0.05-15 wt. % of solid adsorbent; and at least 50 wt. % of water; b) allowing the adsorbent to adsorb lipopolysaccharides; c) separating the solid adsorbent containing adsorbed lipopolysaccharides from the remaining aqueous solution; and d) recovering the biopolymer material containing a reduced level of lipopolysaccharide from the separated aqueous solution.
Public/Granted literature
- US20110168635A1 METHOD FOR REMOVING IMPURITIES FROM BIOPOLYMER MATERIAL Public/Granted day:2011-07-14
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