Invention Grant
- Patent Title: Process for the preparation of anagrelide and analogues
- Patent Title (中): 制备阿那格雷和类似物的方法
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Application No.: US13132001Application Date: 2009-11-30
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Publication No.: US08530651B2Publication Date: 2013-09-10
- Inventor: Bernard Golding
- Applicant: Bernard Golding
- Applicant Address: US KY Florence
- Assignee: Shire LLC
- Current Assignee: Shire LLC
- Current Assignee Address: US KY Florence
- Agency: Lucas & Mercanti, LLP
- Priority: GB0822970.0 20081217
- International Application: PCT/GB2009/051621 WO 20091130
- International Announcement: WO2010/070318 WO 20100624
- Main IPC: C07D487/04
- IPC: C07D487/04

Abstract:
The present invention relates to a novel process for producing quinazoline compounds which are useful in therapy. More specifically, the compounds produced by the process of the invention are useful in the treatment of a number of cardiovascular diseases. The process of the invention provides 6,7-dichloro-1,5-dihydroimidazo[2,1-b]quinazolin 2(3H)-one, more commonly known as anagrelide and its analogues in a clean and efficient manner.
Public/Granted literature
- US20110263850A1 PROCESS FOR THE PREPARATION OF ANAGRELIDE AND ANALOGUES Public/Granted day:2011-10-27
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