Invention Grant
US08530651B2 Process for the preparation of anagrelide and analogues 有权
制备阿那格雷和类似物的方法

  • Patent Title: Process for the preparation of anagrelide and analogues
  • Patent Title (中): 制备阿那格雷和类似物的方法
  • Application No.: US13132001
    Application Date: 2009-11-30
  • Publication No.: US08530651B2
    Publication Date: 2013-09-10
  • Inventor: Bernard Golding
  • Applicant: Bernard Golding
  • Applicant Address: US KY Florence
  • Assignee: Shire LLC
  • Current Assignee: Shire LLC
  • Current Assignee Address: US KY Florence
  • Agency: Lucas & Mercanti, LLP
  • Priority: GB0822970.0 20081217
  • International Application: PCT/GB2009/051621 WO 20091130
  • International Announcement: WO2010/070318 WO 20100624
  • Main IPC: C07D487/04
  • IPC: C07D487/04
Process for the preparation of anagrelide and analogues
Abstract:
The present invention relates to a novel process for producing quinazoline compounds which are useful in therapy. More specifically, the compounds produced by the process of the invention are useful in the treatment of a number of cardiovascular diseases. The process of the invention provides 6,7-dichloro-1,5-dihydroimidazo[2,1-b]quinazolin 2(3H)-one, more commonly known as anagrelide and its analogues in a clean and efficient manner.
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