An auto-sensing switching regulator, and systems and methods including same, is disclosed. The auto-sensing switching regulator includes a switching regulator and a controller coupled thereto. The controller is configured to provide a control signal to the switching regulator to increase the output voltage while receiving a current sense signal representative of a current output of the switching regulator, and to provide the control signal in response to the current sense signal to set the output voltage at a set value corresponding to a value at which the current output stops increasing with an increase in the output voltage. A system to drive a light source includes a current regulator configured to provide a constant current output to the light source and an auto-sensing switching regulator coupled to the current regulator, and configured to receive an input voltage from a voltage supply and provide an output voltage to the current regulator.