An up-right walker for supporting a patient with up-right posture. The up-right walker includes side frames having a back leg frame and a front leg frame. Wheels are coupled to the back leg frame and to front leg frame for contacting a surface for enabling motion. A first support frame is disposed at the top of the first side frame and a second forearm support frame disposed at the top of the second side frame. A first support structure is coupled to the first support frame and a second support structure is coupled to the second forearm support frame. The first and second support structures are configured to have an angled slope not parallel to the surface engaged by the wheels. A knee support fixture may be provided that includes a knee support platform and a pivoting repository for receiving and supporting a knee therein.