Invention Grant
US08540995B2 Monoclonal antibodies specific to the fusion peptide from hemagglutinin from influenza A viruses and uses thereof
有权
来自甲型流感病毒的血凝素的融合肽特异性的单克隆抗体及其用途
- Patent Title: Monoclonal antibodies specific to the fusion peptide from hemagglutinin from influenza A viruses and uses thereof
- Patent Title (中): 来自甲型流感病毒的血凝素的融合肽特异性的单克隆抗体及其用途
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Application No.: US13141160Application Date: 2008-12-24
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Publication No.: US08540995B2Publication Date: 2013-09-24
- Inventor: Prabakaran Mookkan , Nayana Prabhu Padubidhri , Sumathy Velumani , Hwei-Sing Jimmy Kwang
- Applicant: Prabakaran Mookkan , Nayana Prabhu Padubidhri , Sumathy Velumani , Hwei-Sing Jimmy Kwang
- Applicant Address: SG Singapore
- Assignee: Temasek Life Sciences Laboratory Limited
- Current Assignee: Temasek Life Sciences Laboratory Limited
- Current Assignee Address: SG Singapore
- Agency: Rothwell, Figg, Ernst & Manbeck P.C.
- International Application: PCT/SG2008/000499 WO 20081224
- International Announcement: WO2010/074656 WO 20100701
- Main IPC: A61K39/42
- IPC: A61K39/42 ; C12Q1/70 ; C07K16/10

Abstract:
This invention relates to methods and products for the diagnosis, surveillance, prevention, and treatment of influenza A virus infections in animals and humans. More particularly, the invention relates to antibodies and related binding proteins for the detection, prevention and treatment of influenza A viruses. The monoclonal antibodies and related binding proteins of the invention are useful for the treatment of the highly pathogenic H5 subtypes of avian influenza virus (AIV).
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