Invention Grant
- Patent Title: Preparation method of sustained-release microcapsules having initial burst inhibiting property and the microcapsules thereby
- Patent Title (中): 具有初始爆发抑制性能的缓释微胶囊的制备方法和由此产生的微胶囊
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Application No.: US12516275Application Date: 2007-11-21
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Publication No.: US08541030B2Publication Date: 2013-09-24
- Inventor: Nak-Hyun Lim , Jung-Kwoun Kim , Hyung-Joon Jung , Se-Yeon Kim , Goo-Young Jung , Kyung-Hoi Cha , Mork-Soon Park
- Applicant: Nak-Hyun Lim , Jung-Kwoun Kim , Hyung-Joon Jung , Se-Yeon Kim , Goo-Young Jung , Kyung-Hoi Cha , Mork-Soon Park
- Applicant Address: KR Seoul
- Assignee: Dongkook Pharmaceutical Co., Ltd.
- Current Assignee: Dongkook Pharmaceutical Co., Ltd.
- Current Assignee Address: KR Seoul
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: KR10-2006-0117929 20061127
- International Application: PCT/KR2007/005892 WO 20071121
- International Announcement: WO2008/066279 WO 20080605
- Main IPC: A61K9/50
- IPC: A61K9/50

Abstract:
Disclosed is a method for preparing a longer sustained-release formulation containing bioactive substances. More particularly, the present invention provides a method for preparing longer sustained-release microcapsules comprising: adding an emulsion including bioactive substances, biocompatible polymer and polyvinylpyrrolidone to an aqueous solution.
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