Invention Grant
- Patent Title: Genetic modification for production of 3-hydroxypropionic acid
- Patent Title (中): 用于生产3-羟基丙酸的遗传修饰
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Application No.: US13368953Application Date: 2012-02-08
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Publication No.: US08541212B2Publication Date: 2013-09-24
- Inventor: Jae Young Kim , Jae Chan Park , Sung Min Park , Hyun Min Koo , Byung Jo Yu , Hwa Young Cho , Young kyoung Park
- Applicant: Jae Young Kim , Jae Chan Park , Sung Min Park , Hyun Min Koo , Byung Jo Yu , Hwa Young Cho , Young kyoung Park
- Applicant Address: KR Suwon-si, Gyeonggi-do
- Assignee: Samsung Electronics Co., Ltd.
- Current Assignee: Samsung Electronics Co., Ltd.
- Current Assignee Address: KR Suwon-si, Gyeonggi-do
- Agency: Leydig, Voit & Mayer, Ltd
- Priority: KR10-2011-0062312 20110627
- Main IPC: C12P7/62
- IPC: C12P7/62
Abstract:
A method of increasing 3-HP production efficiency by inhibiting expression of a lactate dehydrogenase, a phosphotransacetylase, and an alcohol dehydrogenase in production of 3-HP using a malonic semialdehyde reduction pathway to prevent metabolite leak and increase a malonyl-CoA pool is disclosed.
Public/Granted literature
- US20120329110A1 GENETIC MODIFICATION FOR PRODUCTION OF 3-HYDROXYPROPIONIC ACID Public/Granted day:2012-12-27
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