Invention Grant
- Patent Title: Hydrogen sulfide derivatives of non-steroidal anti-inflammatory drugs
- Patent Title (中): 非甾体抗炎药的硫化氢衍生物
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Application No.: US12704412Application Date: 2010-02-11
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Publication No.: US08541398B2Publication Date: 2013-09-24
- Inventor: John L. Wallace , Giuseppe Cirino , Vincenzo Santagada , Giuseppe Caliendo
- Applicant: John L. Wallace , Giuseppe Cirino , Vincenzo Santagada , Giuseppe Caliendo
- Applicant Address: CA Calgary
- Assignee: Antibe Therapeutics Inc.
- Current Assignee: Antibe Therapeutics Inc.
- Current Assignee Address: CA Calgary
- Agency: Bennett Jones LLP
- Priority: WOPCT/CA2005/000819 20050527
- Main IPC: A61K31/603
- IPC: A61K31/603 ; A61K31/606 ; C07D209/04 ; C07C69/76
Abstract:
The present invention relates to derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) having improved anti-inflammatory properties useful in the treatment of inflammation, pain and fever. More particularly, NSAIDs are derivatized with a hydrogen sulfide (H2S) releasing moiety to produce novel anti-inflammatory compounds having reduced side effects.
Public/Granted literature
- US20100210607A1 HYDROGEN SULFIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY DRUGS Public/Granted day:2010-08-19
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