Invention Grant
- Patent Title: Thiadiazole derivatives for the treatment of neurodegenerative diseases
- Patent Title (中): 噻二唑衍生物用于治疗神经变性疾病
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Application No.: US12187115Application Date: 2008-08-06
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Publication No.: US08541406B2Publication Date: 2013-09-24
- Inventor: Gerard Griffioen , Kristel Marie Edith Coupet , Hein Roger Duhamel , Stefaan Wera , Ellen Gommé , Nele Van Damme , Ingrid Van Der Auwera , Marleen Lox , Tom Van Dooren , Tine Decruy
- Applicant: Gerard Griffioen , Kristel Marie Edith Coupet , Hein Roger Duhamel , Stefaan Wera , Ellen Gommé , Nele Van Damme , Ingrid Van Der Auwera , Marleen Lox , Tom Van Dooren , Tine Decruy
- Applicant Address: BE Heverlee
- Assignee: NV reMYND
- Current Assignee: NV reMYND
- Current Assignee Address: BE Heverlee
- Agency: Clark & Elbing LLP
- Priority: GB0602335.2 20060207; GB0715255.6 20070806; GB0715260.6 20070806; GB0715192.1 20070807
- Main IPC: A61K31/55
- IPC: A61K31/55 ; C07D241/02
Abstract:
This invention provides specifically substituted 1,2,4-thiadiazole derivatives for use in the treatment of an α-synucleopathy such as Parkinson's disease, diffuse Lewy body disease, traumatic brain injury, amyotrophic lateral sclerosis, Niemann-Pick disease, Hallervorden-Spatz syndrome, Down syndrome, neuroaxonal dystrophy, multiple system atrophy and Alzheimer's disease. This invention also provides various methods for producing such substituted 1,2,4-thiadiazole derivatives.
Public/Granted literature
- US20100261707A9 THIADIAZOLE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES Public/Granted day:2010-10-14
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