Invention Grant
- Patent Title: Aminodihydrothiazine derivatives substituted with a cyclic group
- Patent Title (中): 用环状基团取代的氨基二氢噻嗪衍生物
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Application No.: US13417786Application Date: 2012-03-12
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Publication No.: US08541408B2Publication Date: 2013-09-24
- Inventor: Yuusuki Tamura , Shinji Suzuki , Yukio Tada , Chiaki Fujikoshi , Sae Matsumoto , Yuuji Kooriyama
- Applicant: Yuusuki Tamura , Shinji Suzuki , Yukio Tada , Chiaki Fujikoshi , Sae Matsumoto , Yuuji Kooriyama
- Applicant Address: JP Osaka
- Assignee: Shionogi & Co., Ltd.
- Current Assignee: Shionogi & Co., Ltd.
- Current Assignee Address: JP Osaka
- Agency: Hamre, Schumann, Mueller & Larson, P.C.
- Priority: JP2007-114288 20070424; JP2007-290589 20071108
- Main IPC: C07D417/12
- IPC: C07D417/12 ; C07D417/14 ; A61K31/497 ; A61K31/54

Abstract:
This invention provides a compound of the formula (I): wherein the ring A is an optionally substituted carbocyclic group or an optionally substituted heterocyclic group; R1 is optionally substituted lower alkyl, optionally substituted lower alkenyl, optionally substituted lower alkynyl; R2a and R2b are each independently hydrogen, optionally substituted lower alkyl or optionally substituted acyl; R3a, R3b, R3c and R3d are each independently hydrogen, halogen, hydroxy or optionally substituted lower alkyl etc.; a pharmaceutically acceptable salt or solvate thereof, which is useful for treating diseases induced by production, secretion and/or deposition of amyloid β protein.
Public/Granted literature
- US08507479B2 Aminodihydrothiazine derivatives substituted with a cyclic group Public/Granted day:2013-08-13
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