Invention Grant
- Patent Title: Inhibitors of polo-like kinase
- Patent Title (中): 马球激酶抑制剂
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Application No.: US12974622Application Date: 2010-12-21
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Publication No.: US08541418B2Publication Date: 2013-09-24
- Inventor: Robert A. Galemmo , Dean R. Artis , Xiaocong Michael Ye , Danielle Aubele , Anh Truong , Simeon Bowers , Roy K. Hom , Yong-Liang Zhu , R. Jeffrey Neitz , Jennifer Sealy , Marc Adler , Paul Beroza , John P. Anderson
- Applicant: Robert A. Galemmo , Dean R. Artis , Xiaocong Michael Ye , Danielle Aubele , Anh Truong , Simeon Bowers , Roy K. Hom , Yong-Liang Zhu , R. Jeffrey Neitz , Jennifer Sealy , Marc Adler , Paul Beroza , John P. Anderson
- Applicant Address: US CA South San Francisco
- Assignee: Elan Pharmaceutical, Inc.
- Current Assignee: Elan Pharmaceutical, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: A61K31/4965
- IPC: A61K31/4965 ; C07D475/00
Abstract:
The present invention provides compounds having a structure according to Formula (I): or a salt or solvate thereof, wherein ring A, E1, E2, R1, R2, R3 and R4 are defined herein. The invention further provides pharmaceutical compositions including the compounds of the invention and methods of making and using the compounds and compositions of the invention, e.g., in the treatment and prevention of various disorders, such as Parkinson's disease.
Public/Granted literature
- US20110207716A1 INHIBITORS OF POLO-LIKE KINASE Public/Granted day:2011-08-25
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