Invention Grant
- Patent Title: Compounds and methods for reversible modification of biologically active molecules
- Patent Title (中): 用于可逆修饰生物活性分子的化合物和方法
-
Application No.: US12140751Application Date: 2008-06-17
-
Publication No.: US08541548B2Publication Date: 2013-09-24
- Inventor: David B. Rozema
- Applicant: David B. Rozema
- Applicant Address: US WI Madison
- Assignee: Arrowhead Madison Inc.
- Current Assignee: Arrowhead Madison Inc.
- Current Assignee Address: US WI Madison
- Agent Kirk Ekena
- Main IPC: A61K38/00
- IPC: A61K38/00 ; C07K1/00
Abstract:
The present invention is directed compounds for reversibly modification of biologically active molecules. Described are polyconjugates systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery conjugates. The use of reversible modification provides for physiologically responsive activity modulation.
Public/Granted literature
- US20080281074A1 Compounds and Methods for Reversible Modification of Biologically Active Molecules Public/Granted day:2008-11-13
Information query
IPC分类:
