Invention Grant
US08541560B2 Polypeptides comprising Fas activation and NKG2D-ligand domains
有权
包含Fas活化和NKG2D-配体结构域的多肽
- Patent Title: Polypeptides comprising Fas activation and NKG2D-ligand domains
- Patent Title (中): 包含Fas活化和NKG2D-配体结构域的多肽
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Application No.: US12826544Application Date: 2010-06-29
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Publication No.: US08541560B2Publication Date: 2013-09-24
- Inventor: Thomas E. Wagner , Yanzhang Wei
- Applicant: Thomas E. Wagner , Yanzhang Wei
- Applicant Address: US SC Greenville
- Assignee: Thomas E. Wagner
- Current Assignee: Thomas E. Wagner
- Current Assignee Address: US SC Greenville
- Agency: Foley & Lardner LLP
- Main IPC: C07H21/02
- IPC: C07H21/02
Abstract:
The present invention is drawn to fusion proteins comprising (a) a ligand for an NK receptor and (b) a Fas activation domain, and to nucleic acids encoding such fusion proteins. The invention also includes methods of making and using such proteins and nucleic acids, including their use in preventing or treating cancer.
Public/Granted literature
- US20100284975A1 POLYPEPTIDES COMPRISING FAS ACTIVATION AND NKG2D-LIGAND DOMAINS Public/Granted day:2010-11-11
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