Apparatus and methods for reducing output noise of a signal channel are provided. In one embodiment, a signal channel includes an amplifier for amplifying an input signal to generate an amplified signal. The amplifier includes a bias circuit that controls a bias current of the amplifier based on a voltage across a biasing capacitor. The apparatus further includes a sampling circuit for sampling the amplified signal. The sampling circuit generates an output signal based on a difference between a first sample of the amplified signal taken at a first time instance and a second sample of the amplified signal taken at a second time instance. The bias circuit samples a bias voltage onto the biasing capacitor before the first time instance and holds the voltage across the biasing capacitor substantially constant between the first time instance and the second time instance to reduce noise of the output signal.