A method and apparatus for supporting a high-speed mobile terminal in a distributed antenna system. The method includes acquiring information on a position and a speed of each terminal of a plurality of terminals, mapping the plurality of terminals to at least one or more terminal groups based on at least one or more of the position or the speed of the terminal, determining a service end time point at a serving antenna node and a service start time point at a target antenna node, using position and speed information associated with the terminal group, and switching an antenna node for the terminal group, according to the service end time point at the serving antenna node and the service start time point at the target antenna node.