Invention Grant
- Patent Title: Antibodies against domains of laminin-332
- Patent Title (中): 针对层粘连蛋白332结构域的抗体
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Application No.: US13060358Application Date: 2009-06-18
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Publication No.: US08545845B2Publication Date: 2013-10-01
- Inventor: Karl Tryggvason , Sirpa Anne Kristiina Salo
- Applicant: Karl Tryggvason , Sirpa Anne Kristiina Salo
- Agency: Fay Sharpe LLP
- International Application: PCT/IB2009/006404 WO 20090618
- International Announcement: WO2009/153670 WO 20091223
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
Antibodies against various domains of laminin-332 are discussed herein. The antibodies reduce the adhesion and matrix binding properties of laminin-332, inhibiting tumor growth and metastasis in vivo. Pharmaceutical compositions and methods of using the antibodies for diagnostic, prophylactic, and/or therapeutic purposes are disclosed.
Public/Granted literature
- US20110243965A1 ANTIBODIES AGAINST DOMAINS OF LAMININ-332 Public/Granted day:2011-10-06
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