Invention Grant
- Patent Title: Processes for the preparation of phosphatide salts
- Patent Title (中): 制备磷脂盐的方法
-
Application No.: US12700073Application Date: 2010-02-04
-
Publication No.: US08546104B2Publication Date: 2013-10-01
- Inventor: David Rutenberg
- Applicant: David Rutenberg
- Applicant Address: IL Haifa
- Assignee: Lipogen Ltd.
- Current Assignee: Lipogen Ltd.
- Current Assignee Address: IL Haifa
- Agency: FlashPoint IP Ltd.
- Agent Reuven K. Mouallem
- Priority: IL193303 20080807
- Main IPC: C12P1/00
- IPC: C12P1/00

Abstract:
The present invention discloses processes a process for the preparation of phosphatide-salt complexes, the process including the steps of: using at least one raw material lecithin as a substrate; and enzymatically processing at least one raw material lecithin with phospholipase-D, racemic or enantiomerically-pure serine, and/or amine in an aqueous carboxylate-salt-complex solution, wherein the step of processing is performed in a single-phase reaction environment, to produce phosphatide-salt complexes having a structural fatty-acid chain derived from at least one raw material lecithin. Preferably, the step of processing is performed at a pH in the range of about 4.5-8.0 at a temperature in the range of about 25-60° C. Preferably, the aqueous carboxylate-salt-complex solution is formed from an aqueous solution of a carboxylic acid with a chain length of C2-C8 and a salt in an approximately 1:2 (weight per weight) acid-to-salt ratio.
Public/Granted literature
- US20110212922A1 PROCESSES FOR THE PREPARATION OF PHOSPHATIDE SALTS Public/Granted day:2011-09-01
Information query