Invention Grant
- Patent Title: Methods for the production of iPS cells using non-viral approach
- Patent Title (中): 使用非病毒方法生产iPS细胞的方法
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Application No.: US12478154Application Date: 2009-06-04
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Publication No.: US08546140B2Publication Date: 2013-10-01
- Inventor: Amanda Mack , James Thomson
- Applicant: Amanda Mack , James Thomson
- Applicant Address: US WI Madison
- Assignee: Cellular Dynamics International, Inc.
- Current Assignee: Cellular Dynamics International, Inc.
- Current Assignee Address: US WI Madison
- Agency: Parker Highlander PLLC
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/02 ; C12N5/071 ; C12N15/00 ; C12N15/86
Abstract:
Methods and composition of induction of pluripotent stem cells and other desired cell types are disclosed. For example, in certain aspects methods for generating essentially vector-free induced pluripotent stem cells are described. Furthermore, the invention provides induced pluripotent stem cells and desired cell types essentially free of exogenous vector elements with the episomal expression vectors to express differentiation programming factors.
Public/Granted literature
- US20100003757A1 METHODS FOR THE PRODUCTION OF IPS CELLS USING NON-VIRAL APPROACH Public/Granted day:2010-01-07
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