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US08546330B2 Compositions and methods for treatment of neurodegenerative diseases 失效
用于治疗神经变性疾病的组合物和方法

Compositions and methods for treatment of neurodegenerative diseases
Abstract:
Isolated peptides are provided, being less than 20 amino acids in length. The peptides comprising an amino acid sequence GVLYVGSKTREGV (SEQ ID NO: 12) AAATGLVKREE (SEQ ID NO: 13) or GVVAAAEKTKQG (SEQ ID NO: 14), mimetics and/or fragment thereof, the peptides being capable of inhibiting alpha synuclein aggregation. Pharmaceutical compositions comprising same are also provided as well as uses thereof.
Abstract(Chinese):

提供分离的肽，长度小于20个氨基酸。 包含氨基酸序列GVLYVGSKTREGV（SEQ ID NO：12）AAATGLVKREE（SEQ ID NO：13）或GVVAAAEKTKQG（SEQ ID NO：14）的肽，其模拟物和/或片段，所述肽能够抑制α突触核蛋白聚集。 还提供了包含其的药物组合物及其用途。

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