Invention Grant
- Patent Title: Compounds and compositions as kinase inhibitors
- Patent Title (中): 化合物和组合物作为激酶抑制剂
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Application No.: US12865339Application Date: 2009-01-27
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Publication No.: US08546370B2Publication Date: 2013-10-01
- Inventor: Barun Okram , Tetsuo Uno , Qiang Ding , Yahua Liu , Yunho Jin , Qihui Jin , Xu Wu , Jianwei Che , S. Frank Yan , Xueshi Hao
- Applicant: Barun Okram , Tetsuo Uno , Qiang Ding , Yahua Liu , Yunho Jin , Qihui Jin , Xu Wu , Jianwei Che , S. Frank Yan , Xueshi Hao
- Applicant Address: BM Hamilton
- Assignee: IRM LLC
- Current Assignee: IRM LLC
- Current Assignee Address: BM Hamilton
- Agency: Genomics Institute of the Novartis Research Foundation
- Agent Daniel E. Raymond
- International Application: PCT/US2009/032148 WO 20090127
- International Announcement: WO2009/097287 WO 20090806
- Main IPC: A61K31/33
- IPC: A61K31/33

Abstract:
The invention provides a novel class of 2,7-naphthyridin derivatives; pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly Syk, ZAP70, KDR, FMS, FLT3, c-Kit, RET, TrkA, TrkB, TrkC-GR-1R, Alk, c-FMS, or combinations thereof.
Public/Granted literature
- US20110003798A1 COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS Public/Granted day:2011-01-06
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