Invention Grant
- Patent Title: Pharmaceutical compounds
- Patent Title (中): 药物化合物
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Application No.: US13496287Application Date: 2010-09-17
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Publication No.: US08546376B2Publication Date: 2013-10-01
- Inventor: Mark Peter Bell , Timothy Harrison , Sumita Bhattacharyya , James Samuel Shane Rountree , Frank Burkamp , Stephen Price , Calum MacLeod , Richard Leonard Elliott , Phillip Smith , Toby Jonathan Blench , Colin Roderick O'Dowd , Lixin Zhang , Graham Peter Trevitt , Hazel Joan Dyke
- Applicant: Mark Peter Bell , Timothy Harrison , Sumita Bhattacharyya , James Samuel Shane Rountree , Frank Burkamp , Stephen Price , Calum MacLeod , Richard Leonard Elliott , Phillip Smith , Toby Jonathan Blench , Colin Roderick O'Dowd , Lixin Zhang , Graham Peter Trevitt , Hazel Joan Dyke
- Applicant Address: GB Craigavon, Northern Ireland
- Assignee: Almac Discovery Limited
- Current Assignee: Almac Discovery Limited
- Current Assignee Address: GB Craigavon, Northern Ireland
- Agency: Lathrop & Gage LLP
- Agent Brian C. Trinque
- Priority: GB0916458.3 20090918; GB1005734.7 20100406
- International Application: PCT/GB2010/001746 WO 20100917
- International Announcement: WO2011/033265 WO 20110324
- Main IPC: A61K31/4188
- IPC: A61K31/4188 ; A61K31/352 ; A61K31/357 ; A61K31/397 ; A61K31/4155 ; A61K31/4162 ; A61K31/4178 ; A61K31/4192 ; A61K31/422 ; A61K31/436 ; A61K31/437 ; A61K31/496 ; A61K31/5377 ; A61K31/5383 ; A61P35/00 ; C07C225/20 ; C07D311/26 ; C07D405/10 ; C07D413/10 ; C07D491/052 ; C07D491/147 ; C07D493/04 ; C07D498/04
Abstract:
The invention relates to a series of compounds with particular activity as inhibitors of the serine-threonine kinase AKT. Also provided are pharmaceutical compositions comprising same as well as methods for treating cancer.
Public/Granted literature
- US20120238541A1 PHARMACEUTICAL COMPOUNDS Public/Granted day:2012-09-20
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