Invention Grant
US08546398B2 Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses
有权
立体异构富集3-氨基羰基双环庚啶嘧啶二胺化合物及其用途
- Patent Title: Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses
- Patent Title (中): 立体异构富集3-氨基羰基双环庚啶嘧啶二胺化合物及其用途
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Application No.: US11280066Application Date: 2005-11-15
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Publication No.: US08546398B2Publication Date: 2013-10-01
- Inventor: Ankush Argade , Rajinder Singh , Hui Li
- Applicant: Ankush Argade , Rajinder Singh , Hui Li
- Applicant Address: US CA South San Francisco
- Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee: Rigel Pharmaceuticals, Inc.
- Current Assignee Address: US CA South San Francisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Agent Travis Young
- Main IPC: C07D239/48
- IPC: C07D239/48 ; A61K31/506
Abstract:
The present invention provides stereoisomers and stereoisomeric mixtures of 3-aminocarbonyl-bicycloheptene-2,4-pyrimidinediamine compounds having antiproliferative activity, compositions comprising the compounds and methods of using the compounds to inhibit cellular proliferation and to treat proliferate diseases such as tumorigenic cancers.
Public/Granted literature
- US20060167249A1 Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses Public/Granted day:2006-07-27
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