Invention Grant
- Patent Title: Heterocyclic compounds as metap-2 inhibitors
- Patent Title (中): 杂环化合物作为metap-2抑制剂
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Application No.: US13145422Application Date: 2009-12-22
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Publication No.: US08546406B2Publication Date: 2013-10-01
- Inventor: Timo Heinrich , Frank Zenke , Mireille Krier , Kai Schiemann
- Applicant: Timo Heinrich , Frank Zenke , Mireille Krier , Kai Schiemann
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano & Branigan, P.C.
- Priority: DE102009005193 20090120
- International Application: PCT/EP2009/009218 WO 20091222
- International Announcement: WO2010/083870 WO 20100729
- Main IPC: A61K31/519
- IPC: A61K31/519 ; A61K31/52 ; C07D487/14 ; C07D487/22
Abstract:
Compounds of the formula I, in which D, X, Y, Z, R and R1 have the meanings indicated in Claim 1, are inhibitors of methionine aminopeptidase and can be employed for the treatment of tumors.
Public/Granted literature
- US20110281859A1 NOVEL HETEROCYCLIC COMPOUNDS AS METAP-2 INHIBITORS Public/Granted day:2011-11-17
Information query
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