Invention Grant
- Patent Title: Folate receptor binding conjugates of antifolates
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Application No.: US13063889Application Date: 2009-09-17
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Publication No.: US08546425B2Publication Date: 2013-10-01
- Inventor: Christopher Paul Leamon , Iontcho Radoslavov Vlahov , Philip Stewart Low
- Applicant: Christopher Paul Leamon , Iontcho Radoslavov Vlahov , Philip Stewart Low
- Applicant Address: US IN West Lafayette US IN West Lafayette
- Assignee: Purdue Research Foundation,Endocyte, Inc.
- Current Assignee: Purdue Research Foundation,Endocyte, Inc.
- Current Assignee Address: US IN West Lafayette US IN West Lafayette
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- International Application: PCT/US2009/057363 WO 20090917
- International Announcement: WO2010/033733 WO 20100325
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/44 ; C07D239/72

Abstract:
Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described.
Public/Granted literature
- US20110172254A1 FOLATE RECEPTOR BINDING CONJUGATES OF ANTIFOLATES Public/Granted day:2011-07-14
Information query
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