Invention Grant
- Patent Title: Pipecolic linker and its use for chemistry on solid support
- Patent Title (中): 胶体接头及其在固体支持物上的化学应用
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Application No.: US13061080Application Date: 2009-08-28
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Publication No.: US08546533B2Publication Date: 2013-10-01
- Inventor: Jean Martinez , Pawel Zajdel , Maciej Pawlowski , Gilles Subra
- Applicant: Jean Martinez , Pawel Zajdel , Maciej Pawlowski , Gilles Subra
- Applicant Address: FR Paris FR Montpellier PL Kralow FR Montpellier
- Assignee: Centre National de la Recherche Scientifique (CNRS),Universite de Montpellier 1,Universite Jagellone,Universite Montpellier 2—Sciences et Techniques
- Current Assignee: Centre National de la Recherche Scientifique (CNRS),Universite de Montpellier 1,Universite Jagellone,Universite Montpellier 2—Sciences et Techniques
- Current Assignee Address: FR Paris FR Montpellier PL Kralow FR Montpellier
- Agency: Birch, Stewart, Kolasch & Birch, LLP.
- Priority: EP08305512 20080829
- International Application: PCT/EP2009/061171 WO 20090828
- International Announcement: WO2010/023295 WO 20100304
- Main IPC: C07K1/02
- IPC: C07K1/02

Abstract:
The present invention relates to a pipecolic linker and its use as a solid-phase linker in organic synthesis. Said pipecolic solid-phase linker may be used for coupling functional groups chosen between primary amines, secondary amines, aromatic amines, alcohols, phenols and thiols. In particular, said pipecolic solid-phase linker may be used for peptide or pseudopeptide synthesis, such as the reverse N to C peptide synthesis or the retro-inverso peptide synthesis, or for the synthesis of small organic molecules.
Public/Granted literature
- US20110152464A1 PIPECOLIC LINKER AND ITS USE FOR CHEMISTRY ON SOLID SUPPORT Public/Granted day:2011-06-23
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