Invention Grant
- Patent Title: Proteasome inhibitors and methods of using the same
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Application No.: US13249738Application Date: 2011-09-30
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Publication No.: US08546608B2Publication Date: 2013-10-01
- Inventor: Raffaella Bernardini , Alberto Bernareggi , Paolo G. Cassara , Sankar Chatterjee , Germano D'Arasmo , Sergio De Munari , Edmondo Ferretti , Mohamed Iqbal , Ernesto Menta , Patricia A. Messina McLaughlin , Ambrogio Oliva
- Applicant: Raffaella Bernardini , Alberto Bernareggi , Paolo G. Cassara , Sankar Chatterjee , Germano D'Arasmo , Sergio De Munari , Edmondo Ferretti , Mohamed Iqbal , Ernesto Menta , Patricia A. Messina McLaughlin , Ambrogio Oliva
- Applicant Address: US PA Frazer
- Assignee: Cephalon, Inc.
- Current Assignee: Cephalon, Inc.
- Current Assignee Address: US PA Frazer
- Agency: Woodcock Washburn LLP
- Main IPC: C07F5/02
- IPC: C07F5/02

Abstract:
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
Public/Granted literature
- US20120041196A1 Proteasome Inhibitors and Methods of Using the Same Public/Granted day:2012-02-16
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