Methods and related systems are described for the detection of nuclear radiation. The system can include a scintillator material that intrinsically generates radiation and a photodetection system coupled to the scintillator material and adapted to generate electrical signals based on light emitted from the scintillator material. A processing system adapted and programmed to receive the electrical signals, to generate a count rate reference value based at least in part on electrical signals generated in response to the light emitted from the scintillator material due to the intrinsically generated radiation.