The invention discloses a circuit and a method for reducing radio frequency power consumption of mobile phone, wherein a baseband processing chip (21) adjusts a base bias voltage and/or a collector bias voltage of a radio frequency power amplifier (23) according to radio frequency power output of the radio frequency power amplifier (23). Since the invention reduces the radio frequency output power of the radio frequency power amplifier (23) by moderately reducing the base bias voltage and/or the collector bias voltage at the same time when it is ensured that the mobile phone communicates with a base station normally and the linear index and the Adjacent Channel Power Ratio (ACPR) of the radio frequency power amplifier (23) meet the requirements of the specification, thus the efficiency of the radio frequency power amplifier can be improved, the battery energy is saved and the heating problem of the mobile phone is relieved.