An aircraft cockpit with health monitoring system and method enables an occupant (e.g. a pilot) and/or a ground station to monitor the physical condition of the occupant during a flight. A sensor such as a pulse oximetry sensor is in predetermined location to an occupant seat (e.g. an aircraft cockpit seat), within the field of reach of a person seated in the seat. The sensor is supported in the predetermined location in a stable manner that provides sufficient reaction to insertion of a finger to enable insertion of a finger in the sensor while the person is in a seated position, and the sensor is in communication with a control box that processes data from the sensor, and presents the data, e.g. at a the multi functional display in an aircraft cockpit. During a flight, a pilot seated in the aircraft cockpit seat will be prompted to insert a finger into the pulse oximetry sensor to produce output at the multi functional display.