Embodiments of the invention may include systems and methods for notifying a prescriber or other entity of duplicate product prescriptions. According to one embodiment, a method for processing prescriptions is provided that may include the operations of: receiving a healthcare transaction that identifies a current prescribed product, a patient, and a current prescriber who prescribed the current prescribed product; retrieving patient history for the patient; determining the following based on the patient history: that the patient has previously received a previous equivalent product equivalent to the current prescribed product identified in the healthcare transaction and an identity of a previous prescriber of the previous equivalent product; and transmitting a notification to at least one of the previous prescriber or the current prescriber, wherein the notification identifies potential duplicate products.