A method, a system and a computer program of reducing overheads in multiple applications processing are disclosed. The method includes identifying resources interacting with each of the applications from a set of applications and grouping the applications from the set of applications, resulting in at least one application cluster, in response to the identified resources, wherein overheads associated with re-initialization of agents assigned to the identified resources are reduced. The method further includes assigning an agent corresponding to each of the identified resources and initializing the agent corresponding to each of the identified resources. The method further includes identifying parameters associated with the identified resources, pre-processing the identified parameters for each of the identified resources, and also includes selecting a clustering means for the clustering.