The present invention is directed towards systems and methods for the delivery of programming content with targeted advertisements. One embodiment of a method according to the present invention comprises receiving a request for programming content from a given user, determining a given demographic group to which the given user belongs and determining whether the requested programming content is being streamed to one or more users associated with the given demographic group. If the requested programming content is being streamed to one or more users associated with the given demographic group, the requested programming content is streamed with advertisements targeted to the given demographic group to the given user. If not, a new stream is generated for the requested programming content with advertisements targeted to the given demographic group, which is streamed to the given user.