A structural element for use as a brick, construction block, panel, floor or suchlike in the building trade, comprises at least one part made of conglomerate material, such as concrete and suchlike, to which an insert made of insulating or filling material is constrained, to define peripherally at least a connection face for connection to another structural element, the connection face has visible a first surface of the insert and at least a connected second surface of the part made of conglomerate material. On the connection face one or more other structural elements are able to be combined, along a support plane (R, R1, R2) provided in correspondence with the connection face, so as to be laid and stably connected by means of a layer of binder material. The second surface has a seating made longitudinally and lowered with respect to the support plane (R, R1, R2), on which seating the layer of binder material is located. The seating has a determinate depth (D), with respect to the support plane (R, R1, R2). The depth (D) is correlated to the predefined thickness of the binder material to be laid.