Method of modulating HSF-1

Invention Grant

US08551726B2 Method of modulating HSF-1 有权

Title translation: 调节HSF-1的方法

Patent Title: Method of modulating HSF-1
Patent Title (中): 调节HSF-1的方法
Application No.: US13155170

Application Date: 2011-06-07
Publication No.: US08551726B2

Publication Date: 2013-10-08
Inventor: Richard I. Morimoto , Sandy Westerheide , Julius Anckar , Lea Sistonen , Barbara Calamini
Applicant: Richard I. Morimoto , Sandy Westerheide , Julius Anckar , Lea Sistonen , Barbara Calamini
Applicant Address: US IL Evanston
Assignee: Northwestern University
Current Assignee: Northwestern University
Current Assignee Address: US IL Evanston
Agency: Casimir Jones, S.C.
Main IPC: C12Q1/34
IPC: C12Q1/34

Abstract:

The present invention is directed to methods of modulating HSF1 activity comprising modifying the acetylation of the DNA binding domain of the HSF1.

Abstract(Chinese):

本发明涉及调节HSF1活性的方法，包括修饰HSF1的DNA结合结构域的乙酰化。

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IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12Q	包含酶、核酸或微生物的测定或检验方法（免疫检测入G01N33/53）；其所用的组合物或试纸；这种组合物的制备方法；在微生物学方法或酶学方法中的条件反应控制
C12Q1/00	包含酶、核酸或微生物的测定或检验方法（带有条件测量或传感器的测定或试验装置，如菌落计数器入C12M1/34）；其组合物；这种组合物的制备方法
C12Q1/34	.包括水解酶