Invention Grant
- Patent Title: Vault complexes for facilitating biomolecule delivery
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Application No.: US12950994Application Date: 2010-11-19
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Publication No.: US08551781B2Publication Date: 2013-10-08
- Inventor: Leonard H. Rome , Valerie A. Kickhoefer , Glen R. Nemerow , Cheng-Yu Lai , Christopher M. Wiethoff , Mu Ri Han
- Applicant: Leonard H. Rome , Valerie A. Kickhoefer , Glen R. Nemerow , Cheng-Yu Lai , Christopher M. Wiethoff , Mu Ri Han
- Applicant Address: US CA Oakland US CA La Jolla
- Assignee: The Regents of the University of California,The Scripps Research Institute
- Current Assignee: The Regents of the University of California,The Scripps Research Institute
- Current Assignee Address: US CA Oakland US CA La Jolla
- Agency: Fenwick & West LLP
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/07
Abstract:
The invention relates to compositions of vault complexes containing recombinant membrane lytic proteins, such as an adenovirus protein VI lytic domain, and methods of using the vault complexes to facilitate delivery and entry of a biomolecule into a cell or subject.
Public/Granted literature
- US20110201112A1 Vault Complexes for Facilitating Biomolecule Delivery Public/Granted day:2011-08-18
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