Invention Grant
- Patent Title: Benzodioxane inhibitors of leukotriene production
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Application No.: US13418377Application Date: 2012-03-13
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Publication No.: US08551982B2Publication Date: 2013-10-08
- Inventor: Asitha Abeywardane , Michael J. Burke , Thomas Martin Kirrane , Matthew Russell Netherton , Anil Kumar Padyana , Lana Louise Smith Keenan , Hidenori Takahashi , Michael Robert Turner , Qiang Zhang , Qing Zhang
- Applicant: Asitha Abeywardane , Michael J. Burke , Thomas Martin Kirrane , Matthew Russell Netherton , Anil Kumar Padyana , Lana Louise Smith Keenan , Hidenori Takahashi , Michael Robert Turner , Qiang Zhang , Qing Zhang
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; David L. Kershner
- Main IPC: A61K31/553
- IPC: A61K31/553 ; A61K31/55 ; A61K31/551 ; A61K31/438 ; A61K31/436 ; A61K31/453 ; A61K31/5377 ; A61K31/40 ; A61K31/4025 ; A61K31/357 ; C07D267/08 ; C07D225/02 ; C07D243/08 ; C07D245/02 ; C07D221/20 ; C07D491/04 ; C07D401/02 ; C07D413/14 ; C07D405/14 ; C07D405/02 ; C07D319/16
Abstract:
The present invention relates to compounds of formula (I): wherein R1 to R3, A, X and n are as defined herein. The compounds of formula (I) are useful as inhibitors of leukotriene A4 hydrolase (LTA4H) and treating LTA4H related disorder. The present invention also relates to pharmaceutical compositions comprising the compounds of formula (I), methods of using these compounds in the treatment of various diseases and disorders, and processes for preparing these compounds.
Public/Granted literature
- US20130196973A1 BENZODIOXANE INHIBITORS OF LEUKOTRIENE PRODUCTION Public/Granted day:2013-08-01
Information query
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