Invention Grant
US08552003B2 (S)-N-((S)-1-cyclohexyl-2-{(S)-2-[4-4-(4-fluorobenzoyl)-thiazol-2-yl]pyrrolidin-1-yl}-2-oxoethyl)-2-methylamino-propionamide, or pharmaceutically acceptable salts thereof and their uses
有权
(S)-N - ((S)-1-环己基-2 - {(S)-2- [4-4-(4-氟苯甲酰基) - 噻唑-2-基]吡咯烷-1-基} -2- 氧代乙基)-2-甲基氨基 - 丙酰胺或其药学上可接受的盐及其用途
- Patent Title: (S)-N-((S)-1-cyclohexyl-2-{(S)-2-[4-4-(4-fluorobenzoyl)-thiazol-2-yl]pyrrolidin-1-yl}-2-oxoethyl)-2-methylamino-propionamide, or pharmaceutically acceptable salts thereof and their uses
- Patent Title (中): (S)-N - ((S)-1-环己基-2 - {(S)-2- [4-4-(4-氟苯甲酰基) - 噻唑-2-基]吡咯烷-1-基} -2- 氧代乙基)-2-甲基氨基 - 丙酰胺或其药学上可接受的盐及其用途
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Application No.: US12376057Application Date: 2007-07-31
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Publication No.: US08552003B2Publication Date: 2013-10-08
- Inventor: Mark G. Charest , Christine Hiu-Tung Chen , Zhuoliang Chen , Miao Dai , Feng He , Huangshu Lei , Ly Luu Pham , Sushil Kumar Sharma , Christopher Sean Straub , Run-Ming David Wang , Fan Yang , Leigh Zawel
- Applicant: Mark G. Charest , Christine Hiu-Tung Chen , Zhuoliang Chen , Miao Dai , Feng He , Huangshu Lei , Ly Luu Pham , Sushil Kumar Sharma , Christopher Sean Straub , Run-Ming David Wang , Fan Yang , Leigh Zawel
- Applicant Address: CH Basel
- Assignee: Novartis AG
- Current Assignee: Novartis AG
- Current Assignee Address: CH Basel
- Agent Arlene K. Musser
- International Application: PCT/US2007/074790 WO 20070731
- International Announcement: WO2008/016893 WO 20080207
- Main IPC: A01N43/54
- IPC: A01N43/54
![(S)-N-((S)-1-cyclohexyl-2-{(S)-2-[4-4-(4-fluorobenzoyl)-thiazol-2-yl]pyrrolidin-1-yl}-2-oxoethyl)-2-methylamino-propionamide, or pharmaceutically acceptable salts thereof and their uses](/abs-image/US/2013/10/08/US08552003B2/abs.jpg.150x150.jpg)
Abstract:
The present invention is directed to a compound of the formula: or pharmaceutically acceptable salts thereof and use of such compounds for treating proliferative diseases such as cancer, in mammals.
Public/Granted literature
- US20110065726A1 Organic Compounds Public/Granted day:2011-03-17
Information query
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