Invention Grant
US08552023B2 Non-amidic linkers with branched termini as CGRP receptor antagonists
有权
具有支链末端的非酰胺接头作为CGRP受体拮抗剂
- Patent Title: Non-amidic linkers with branched termini as CGRP receptor antagonists
- Patent Title (中): 具有支链末端的非酰胺接头作为CGRP受体拮抗剂
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Application No.: US13059361Application Date: 2009-08-11
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Publication No.: US08552023B2Publication Date: 2013-10-08
- Inventor: Michael R. Wood , June J. Kim , Harold G. Selnick , Shawn J. Stachel
- Applicant: Michael R. Wood , June J. Kim , Harold G. Selnick , Shawn J. Stachel
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Nicole M. Beeler; John C. Todaro
- International Application: PCT/US2009/053334 WO 20090811
- International Announcement: WO2010/021864 WO 20100225
- Main IPC: A61K31/437
- IPC: A61K31/437 ; C07D471/10 ; C07D471/20 ; A61P29/00 ; A61P25/06 ; A61P9/12
Abstract:
The present invention is directed to novel non-amidic linkers with branched termini derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Public/Granted literature
- US20110190329A1 NON-AMIDIC LINKERS WITH BRANCHED TERMINI AS CGRP RECEPTOR ANTAGONISTS Public/Granted day:2011-08-04
Information query
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