Invention Grant
- Patent Title: 7-substituted indirubin-3′oximes and their applications
- Patent Title (中): 7-取代的靛玉红-3'-肟及其应用
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Application No.: US12086984Application Date: 2006-12-21
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Publication No.: US08552053B2Publication Date: 2013-10-08
- Inventor: Laurent Meijer , Karima Bettayeb , Alexios-Le-Andros Skaltsounis , Prokopios Maglatis , Jacint Boix , Judit Ribas
- Applicant: Laurent Meijer , Karima Bettayeb , Alexios-Le-Andros Skaltsounis , Prokopios Maglatis , Jacint Boix , Judit Ribas
- Applicant Address: FR Paris Cedex FR Paris Cedex FR Rennes Cedex ES Lleida GR Athens
- Assignee: Centre National de la Recherche Scientifique,University of Pierre and Marie Curie (Paris 6),University of Rennes 1,University of Lleida,Universite d'Athenes
- Current Assignee: Centre National de la Recherche Scientifique,University of Pierre and Marie Curie (Paris 6),University of Rennes 1,University of Lleida,Universite d'Athenes
- Current Assignee Address: FR Paris Cedex FR Paris Cedex FR Rennes Cedex ES Lleida GR Athens
- Agency: Nixon & Vanderhye P.C.
- International Application: PCT/IB2006/004152 WO 20061221
- International Announcement: WO2007/099402 WO 20070907
- Main IPC: A61K31/40
- IPC: A61K31/40 ; C09B7/04
Abstract:
The invention relates to new 3′-, 7-substituted-indirubins of formula (I) wherein R represents N—OH, N—O-alkyl or N—O—CO-alkyl, NO—(Ra)n1-Het, N—O—(Y)n1—N Ra Rb, N—O—CO—N(Rb Rc), radical with Het representing an aliphatic nitrogeneous heterocycle, Y being an optionally substituted —CH2— radical, n1 being 1 to 3, and X is an halogen atom selected in the group comprising F, Cl, Br, I, and Z is H or CH3 and the salts thereof.
Public/Granted literature
- US20100331327A1 7-SUBSTITUTED INDIRUBIN-3'OXIMES AND THEIR APPLICATIONS Public/Granted day:2010-12-30
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