Invention Grant
- Patent Title: Anti-PD-L1 antibodies and uses therefor
- Patent Title (中): 抗PD-L1抗体及其用途
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Application No.: US13120406Application Date: 2009-09-25
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Publication No.: US08552154B2Publication Date: 2013-10-08
- Inventor: Gordon J. Freeman , Rafi Ahmed , Timothy D. Jones , Francis J. Carr , James P. Gregson
- Applicant: Gordon J. Freeman , Rafi Ahmed , Timothy D. Jones , Francis J. Carr , James P. Gregson
- Applicant Address: US GA Atlanta US MA Boston
- Assignee: Emory University,Dana-Farber Cancer Institute, Inc.
- Current Assignee: Emory University,Dana-Farber Cancer Institute, Inc.
- Current Assignee Address: US GA Atlanta US MA Boston
- Agency: Morrison & Foerster LLP
- International Application: PCT/US2009/058475 WO 20090925
- International Announcement: WO2010/036959 WO 20100401
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395
Abstract:
The present invention is based, in part, on the identification of novel human anti-PD-1, PD-L1, and PD-L2 antibodies. Accordingly, the invention relates to compositions and methods for diagnosing, prognosing, and treating conditions that would benefit from modulating PD-1, PD-L1, and/or PD-L2 activity (e.g., persistent infectious diseases, autoimmune diseases, asthma, transplant rejection, inflammatory disorders and tumors) using the novel human anti-PD-1, PD-L1, and PD-L2 antibodies described herein.
Public/Granted literature
- US20110271358A1 HUMAN ANTI-PD-1, PD-L1, AND PD-L2 ANTIBODIES AND USES THEREFOR Public/Granted day:2011-11-03
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