Invention Grant
US08552168B2 Nucleic acids for inducing expression of transcripts and proteins and methods for making and using them
有权
用于诱导转录物和蛋白质表达的核酸及其制备和使用方法
- Patent Title: Nucleic acids for inducing expression of transcripts and proteins and methods for making and using them
- Patent Title (中): 用于诱导转录物和蛋白质表达的核酸及其制备和使用方法
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Application No.: US12599577Application Date: 2008-05-08
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Publication No.: US08552168B2Publication Date: 2013-10-08
- Inventor: Steven P. Briggs , Kiyoshi Tachikawa
- Applicant: Steven P. Briggs , Kiyoshi Tachikawa
- Applicant Address: US CA Oakland
- Assignee: The Regents of the University of California
- Current Assignee: The Regents of the University of California
- Current Assignee Address: US CA Oakland
- Agency: Gavrilovich, Dodd & Lindsey LLP
- Agent Gregory P. Einhorn
- International Application: PCT/US2008/063081 WO 20080508
- International Announcement: WO2008/141096 WO 20081120
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N15/00 ; C12N15/82 ; C12N15/74 ; C12N1/20 ; C12N1/00 ; C12N1/12 ; C12P21/06
Abstract:
The invention provides nucleic acids and polypeptides for enhanced expression of nucleic acids and proteins. In one aspect, the sequences serve as transcription and translation enhancers or stabilizers, and can be incorporated in expression constructs at or near the translation control elements. The invention provides methods of producing mRNA (transcripts) and proteins. The invention provides methods of discovering new enhancer elements.
Public/Granted literature
- US20100306880A1 NUCLEIC ACIDS FOR INDUCING EXPRESSION OF TRANSCRIPTS AND PROTEINS AND METHODS FOR MAKING AND USING THEM Public/Granted day:2010-12-02
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