Invention Grant
- Patent Title: Therapeutic agent for Alzheimer's disease
- Patent Title (中): 阿尔茨海默病治疗剂
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Application No.: US12994472Application Date: 2009-05-27
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Publication No.: US08552220B2Publication Date: 2013-10-08
- Inventor: Hachiro Sugimoto , Takashi Takahashi , Ichiro Hijikuro , Michiaki Okuda
- Applicant: Hachiro Sugimoto , Takashi Takahashi , Ichiro Hijikuro , Michiaki Okuda
- Applicant Address: JP Tokyo JP Kyoto
- Assignee: Tokyo Institute of Technology,Kyoto University
- Current Assignee: Tokyo Institute of Technology,Kyoto University
- Current Assignee Address: JP Tokyo JP Kyoto
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: JP2008-141996 20080530
- International Application: PCT/JP2009/059675 WO 20090527
- International Announcement: WO2009/145219 WO 20091203
- Main IPC: C07C49/248
- IPC: C07C49/248

Abstract:
To develop a highly safe measure to treat Alzheimer's disease using a secretase-inhibiting substance, there is provided a compound represented by the following general formula (I) or a salt thereof: wherein A represents a phenyl group or the like, R1 represents a chlorine atom, a bromine atom, or a nitro group or the like, R2, R3, R4, and R5 each represent a hydrogen atom or the like, and L represents CH2—CH2 or CH═CH.
Public/Granted literature
- US20110082295A1 NOVEL CURCUMIN DERIVATIVE Public/Granted day:2011-04-07
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