A method of operating a wireless communication system comprises making a determination which of plural transmission modes is to be a selected transmission mode for transmitting plural entities to a receiving node over a radio interface, and then (at a network coding node (24)) in accordance with the determination implementing the selected transmission mode with respect to the plural input entities. The plural transmission modes include at least two of: (1) an analog network-coded mode wherein plural input signals provided to a network coding node are network-combined by signal interference at a signal level at the network coding node into one analog network-combined output entity; (2) a digital network-coded mode wherein the plural input entities provided to the network coding node are network-combined by operation at a bit level at the network coding node into one or plural digital network-combined output entities; (3) a symbol level network-coded mode wherein the plural input entities are already modulated and network coding is performed on the already modulated plural input entities; and (4) a separate transmission mode wherein the plural input entities provided to the network coding node leave the network coding node as respective plural uncombined output entities.