Systems, methods, and computer readable media for managing digital media in a memory storage device associated with a mobile smart device are disclosed. According to one aspect, the subject matter described herein includes a method for configuring a rewriteable non-volatile memory for presentation of media by a selected media presentation device model. The method includes providing a rewriteable non-volatile memory configuration interface through which a user can select at least one media file and one of a plurality of media presentation device models. and providing a rewriteable non-volatile memory configuration manager, which, in response to selection of the at least one media file and the one media presentation device model via the configuration interface, accesses a database including entries corresponding to the plurality of media presentation device models and configures a rewriteable non-volatile memory according to information retrieved from the database to allow presentation of the at least one media file when the rewriteable non-volatile memory is present in the selected media presentation device model.