A method and apparatus to address multipath interference in a communication system is provided. The method comprises measuring an error signal in a signal path of the repeater, wherein the error signal contains desired communication signals, noise signals, and multipath coupling interference signals, computing a power spectrum of the measured error signal, and estimating a response of the multipath coupling interference by processing the power spectrum of the measured error signal using autoregressive estimation in the frequency domain. The method further comprises computing a plurality of FIR filter coefficients from the estimated response and applying the plurality of filter coefficients to an adjustable filter that generates a cancellation signal used to at least partially mitigate the multipath coupling interference signals.