An automated audio tuning system may optimize an audio system for power efficiency when performing automated tuning of the audio system to optimize acoustic performance. The system may establish any number of different power efficiency weighting factors to provide a balance between acoustic performance and power efficiency during operation. The power efficiency weighting factors may range from representing optimizing power efficiency with constrained optimization of acoustic performance to optimized acoustic performance with minimized regard for power efficiency. For each of the efficiency weighting factors, the system may generate operational parameters, such as filter parameters, to achieve a target acoustic response while maintaining a determined level of power efficiency.