Embodiments disclosed enable the detection of the presence of chemical, biological, and/or explosive (CBE) substance or other items of interest on individuals handling tickets, fobs, passes, smartcards, or other media. Embodiments generally contemplate issuing media at a first location and analyzing the media at a second location. Material sensitive to CBE substance can be applied to the media at the first and/or second location. An adhesive also may be used to attract and/or retain particles to the media for analysis and/or adhere the detection material to the media. Such embodiments can be utilized in airports, transit stations, and other applications where security against threats posed by CBE substance may be a concern.